The Genetic Puzzle of Familial Atrial Fibrillation

Atrial fibrillation (AF) is the most common progressive tachyarrhythmia. In Europe, AF is expected to reach a prevalence of 18 million by 2060. This estimate will increase hospitalization for AF to 4 million and 120 million outpatient visits. Besides being an independent risk factor for mortality, AF is also associated with an increased risk of […]

genetic puzzle of familial atrial fibrillation

Innovative Approaches to Treat Atrial Fibrillation: From Bench to Bedside

Guest Editors: Prof. Bianca Brundel AmsterdamUMC and founder of AFIP, and Dr. Xun Ai, Rush University Chicago Atrial fibrillation (AF), the most common progressive cardiac rhythm disorder, is present in 2-3% of the Western population and associated with common risk factors, such as advanced age, hypertension, diabetes and obesity. As AF may result in serious [...]

Atrial Tissue Conductivity Estimation For Analysis of Atrial Fibrillation

The Electrical Circuit of The Heart Have you ever considered your heart as an electrical circuit? That is how we,  electrical engineers at TU Delft, look at the heart. To us, Atrial Fibrillation (AF) is a fault in the heart circuit and the first step in finding faults on a circuit is to perform some [...]
Bahareh Abdikivanani researching atrial fibrillation

(ENGELS) Atrial fibrillation causes DNA damage and energy depletion in the heart

Atrial Fibrillation (AF) is the most common clinical tachyarrhythmia with a strong tendency to progress in time. AF progression is driven by derailment of protein homeostasis, which ultimately causes electrical conduction changes and contractile dysfunction of the atria. New research published in Nature Communications by the group of Prof. Bianca Brundel (VUmc) in collaboration with [...]